Preexisting Diabetes Elevates Risk of Local and Systemic Complications in Acute Pancreatitis
نویسندگان
چکیده
منابع مشابه
Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis.
BACKGROUND & AIMS Protease-activated receptor 2 can be stimulated by interstitially released trypsin during acute inflammation of the pancreas. In this study, we investigated the roles of pancreatic and circulatory protease-activated receptor 2 in the pathogenesis of acute pancreatitis by using in vitro and in vivo model systems. METHODS Physiological and pathologic effects of protease-activa...
متن کاملCompartmentalization of the inflammatory response during acute pancreatitis: correlation with local and systemic complications.
Local and systemic inflammation has been implicated in the pathogenesis of acute pancreatitis and secondary multisystem organ failure. To assess the pro- and antiinflammatory response, the site of mediator production, and their route of diffusion, we sampled simultaneously ascites, thoracic lymph, and blood at the onset of end-organ dysfunction and for the following 6 days in 60 patients with a...
متن کاملComplications of Acute Pancreatitis
IntroductIon Acute pancreatitis is an acute inflammatory process of the pancreas, which has variable involvement of other regional tissues and/or remote organ systems. The disease can be classified as mild or severe depending on the extent of inflammation and organ involvement. Mild pancreatitis consists of interstitial (edematous) pancreatitis on imaging with minimal or no extrapancreatic orga...
متن کاملPrevalence of Complications of Diabetes and Risk Factors Among Patients with Diabetes in the Diabetes Clinic in Southeast of Iran
Objective: Academic health services play an important role in the prevention and control of diabetes mellitus (DM) in Iran. This study aimed at determining the prevalence of DM-related complications and the associated risk factors among patients with DM in a university-affiliated outpatient diabetes clinic of a referral hospital in Southeast of Iran, Zahedan. Materials and Methods: This cross-...
متن کاملLung complications in acute pancreatitis.
CONTEXT Severe acute pancreatitis has long been known to be a cause of pulmonary dysfunction and multisystem organ failure. OBJECTIVE We evaluated the spectrum of pulmonary dysfunction in acute pancreatitis. METHODS Over a period of one year, 60 patients referred to us with a diagnosis of acute pancreatitis on the basis of clinical findings, CT and elevated serum amylase level were studied ...
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ژورنال
عنوان ژورنال: Pancreas
سال: 2018
ISSN: 1536-4828,0885-3177
DOI: 10.1097/mpa.0000000000001122